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Stručni članak
EFEKTI GLUCOSAMINE SULFATE® I FLEX-A-MIN COMPLEXA® NA PARAMETRE OPORAVKA NAKON POVREDA LOKOMOTORNOG SISTEMA
Sergej M. Ostojić, Nenad Dikić, Jasmina Vuković, Ivan Lukić,
Slobodan Prodanović, Miodrag Arsić, Nebojša Antić, Andraš Mađar,
Miodrag Zlatanović, Dragan Milović , Milovan Erić, Bojan Lazić
Sažetak
Ciljevi ove studije su bili determinisanje efekata koje ima unos Glucosamine Sulfate i Flexamin Complex na trajanje oporavka nakon povreda koštano-zglobnog sistema i formiranje preporuka za adekvatan unos preparata kod sportskih trauma koštano-zglobnog sistema. Studija je bila prospektivna, multicentrična i obuhvatila je ispitanike (n = 181) koji su doživeli akutnu povredu lokomotornog sistema. Ispitanici koji su doživeli povredu su biti podeljeni u tri grupe: grupa I - Glucosamine Sulfate (3 x 1 kapsulu), grupa II - Glucosamine Sulfate (2 x 1 kapsulu) i Flexamin Complex (1 x 1 tabletu), grupa III - nesterodni anti-inflamatorni lekovi (NSAIL). Kontrolni pregledi su se izvodili nakon 7, 14, 21 i 28 dana od povrede. Praćeni su sledeći parametri - trajanje oporavka u danima, intenzitet bola, obim povređenog zgloba, goniometrijski obim pokretljivosti zahvaćenog zgloba, stepen palpatorne osetljivosti traumatizovanog tkiva i popunjavan je standardni upitnik KOOS skale koji je skorovana prema preporukama (Roos et al. 1998). Kod distorzije skočnog zgloba, značajno manji bol pri palpaciji prisutan je nakon 21 dan u II grupi i nakon 28 dana u obe eksperimentalne grupe u poređenju sa ispitanicima koji su unosili NSAIL (p < 0.05). KOOS skorovanje pokazalo je da kompletniji oporavak imaju ispitanici iz I i II eksperimentalne grupe nakon 28 dana u odnosu na ispitanike koji su uzimali NSAIL (p < 0.05). Indeks otoka skočnog zgloba je značajno manji kod II grupe nakon 28 dana (p < 0.05). Upotreba glukozamina i hondroitin sulfata nakon akutne sportske povrede lokomotornog sistema skraćuje trajanje oporavka, smanjuje osećaj bola pri miru i pokretu i povećava obim pokretljivosti zglobova u poređenju sa upotrebom nesteroidnih anti-inflamatornih lekova. Korisni efekti uzimanja uočavaju se pri produženom davanju (od 3 nedelje) i efekti su veći ukoliko se glukozamin kombinuje sa hondroitin sulfatom.
Ključne reči: hondroprotektivi, sportska povreda, oporavak
The effectts of Glucosamine Sulfate and Flex-a-min Complex
on recovery after acute injury of musculoskeletal system
Abstract
The purpose of the present study was to determine the effects of Glucosamine Sulfate and Flexamin Complex on recovery time after acute sports injury of musculoskeletal system and establish the intake guidelines in sports medicine and traumatology. During the study we analyzed subjects (n = 181) with acute injury of musculoskeletal system. Subjects were allocated to three groups. During the 30 days, subjects from group I ingested Glucosamine Sulfate (3 x 1 caps), from group II Glucosamine Sulfate (2 x 1 caps) and Flexamin Complex (1 x 1 tabs) and from group III non-steroid anti-inflamatory drugs (NSAID). Subject went to regular clinical examination after 7, 14, 21 and 28 days after the injury. We assessed the following parameters - fucntional recovery time, pain scale level, injured tissue circumference, degree of sensitivity, range of motion and KOOS index after guidelines (Roos et al. 1998). We found significantly lower intensity of pain in subjects with ankle sprain who ingested glucosamine (after 28 days) and both glucosamine and flexamine (after 21 and 28 days) as compared to subjects who ingested NSAID (p < 0.05). KOOS score showed improved recovery in subjects from I and II group after 28 days as comapred to subjects who ingested NSAID (p < 0.05). The ankle swelling index was significantly lower in group I and II after 28 days (p < 0.05). The use fo glucosamine and hondroitine sulfate after acute sports injury significantly reduced recovery time, decereased pain in rest and motion and improved range of motion as comapred to intake of NSAID. The beneficial effects are shown with prolonged intake (3 weeks or more) and effects are improved with combination of both hondroprotective products.
Key words: hondroprotective, sports injury, recovery
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